The Expert Working Group re-evaluated the data supporting the Cadmium inhalation PDE and concluded that a modifying factors approach, similar to that used for calculating the oral and parenteral PDEs, was appropriate for the inhalation PDE. The corrected value resulted in 3.4 μg/day.
Cadmium (Cd) |
|||
|
Oral |
Parenteral |
Inhalation |
PDE (μg/day) |
5.0 |
1.7 |
3.4 |
Comments on the ICH Q3D(R1) draft revision document can be entered by e-mail to the ICH Secretariat. More details can be found under the Public Consultation page.
Source:
ICH: Newsroom
Write a comment on this news.